Basically, even when evidence-based medicine shows certain treatments and supplements don’t work, some people will continue to cling to them.
Glucosamine is one of these. It’s been extensively, thoroughly debunked as a cartilage regrower, as a pain reliever, as a function improver, but you throw a rock at a Bad Knees Convention, and you’ll hit about twenty people who swear by it. Some will say they can’t leave the house before taking their glucosamine tablet. (My standard disclaimer applies here: if glucosamine helps you, and you’re fine coughing up the money for it, go right ahead. But of course, I also believe if taping a piece of pink construction paper to your nose helps with your knee pain, that’s fine too.)
Another belief that is less widespread regards vitamin D supplements, and their beneficial effect on knee pain. When I wrote this post, I was taking vitamin D myself (not related to knee pain, which I no longer have, but rather for general health reasons). Nowadays the vitamin D fad is kind of burning out, and taking high doses has been shown to cause problems.
Yet I’m willing to bet there are still holdouts when it comes to using vitamin D to treat knee pain. So in their honor, I bring you this study, which is about a year old. The lead of this summary about it:
Vitamin D, which can reduce bone turnover and cartilage degradation, did not slow progression of knee osteoarthritis (OA) or reduce knee OA pain when tested in a randomized placebo-controlled trial.The study included 413 patients who were considered vitamin D deficient. So, if anyone would see an improvement from taking the vitamin, presumably they would. For two years they took vitamin D (or didn’t if they were in the placebo group). Then MRIs were done and pain scores taken.
The authors concluded:
Results showed that even among study participants with low 25-hydroxyvitamin D, supplementation did not slow cartilage loss or improve WOMAC-assessed pain. These data suggest a lack of evidence to support vitamin D supplementation for slowing disease progression or structural change in knee osteoarthritis.Fun bit of trivia: The lead researcher on this study was Changhai Ding, who also did the very first study I came across that really buoyed my hopes when I had knee problems. I mention that study in the book: it showed cartilage defects were found to improve about as often as they got worse over a two-year period. Fascinating, amazing, uplifting!